The Journal of Phytopharmacology 2025; 14(1):55-61 ; DOI:10.31254/phyto.2025.14108
A review of pharmacology, toxicology and phytochemical composition of Cassipourea malosana (Rhizophoraceae)
Dennis Jack Opwoko1 , Joseph Mwanzia Nguta2 , Isaac Ole Mapenay3
1. Head of Department, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Mount Kenya University, P.O. Box 342-01000, Thika, Kenya
2. Associate Professor, Department of Public Health, Pharmacology and Toxicology, College of Veterinary and Agricultural Sciences, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya
3. Senior Lecturer, Department of Public Health, Pharmacology and Toxicology, College of Veterinary and Agricultural Sciences, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya
*Author to whom correspondence should be addressed.
Received: 26th December, 2024 / Accepted: 22nd February, 2025 / Published : 23rd March, 2025
Plants have served as a rich source of bioactive compounds leading to their utilization in folk medicine for a variety of diseases. Plants have also been explored in development of synthetic drugs. In contrast to plants benefit in management of various conditions, they have toxic compounds and the safety of these plants is not extensively analysed for toxicity profile. In addition, the mechanism of action, pharmacokinetics, bioavailability, synergistic effects and clinical validation data on plants are still under-researched. This review article explores the pharmacology, toxicology and phytochemical composition of Cassipourea malosana (Rhizophoraceae) documented in manifold journals and articles. This review article has been created with the assistance of articles, books, peer reviewed articles, validated internet sources, theses, Science Direct and Google Scholar. Cassipourea malosana (Rhizophoraceae) has been employed in treatment of various disease like: stomach ailments, wound healing, treatment of fever and relieve of headache. Hence, these uses can be attributed to diversity of phytochemical constituents including but not limited to tannins, alkaloids, flavonoids and saponins. Cassipourea malosana (Rhizophoraceae) pharmacology and toxicology have not been extensively studied. Further studies are needed to demonstrate additional phytochemical constituents, pharmacological activities and toxicity profiles. Cassipourea malosana (Rhizophoraceae) will provide new medication in the management of diseases to supplement conventional drugs which have been linked to various adverse effects during their use.
Rhizophoraceae, Cassipourea malosana, Pharmacology, Phytochemical composition, Phytochemical toxicity
HOW TO CITE THIS ARTICLE
Opwoko DJ, Nguta JM, Mapenay IO. A review of pharmacology, toxicology and phytochemical composition of Cassipourea malosana (Rhizophoraceae). J Phytopharmacol 2025; 14(1):55-61. doi: 10.31254/phyto.2025.14108
Creative Commons (CC) License-
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY 4.0) license. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. (http://creativecommons.org/licenses/by/4.0/).
Copyright
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0.